Jessica Bradley

From Memory Alpha, the free Star Trek reference.

Jessica Bradley was a hologram in one of Picard's Dixon Hill holonovels. Jessica claimed that someone was trying to kill her, and therefore she wanted to hire Dixon Hill (in the holodeck played by Picard).

After reading the San Francisco Herald, Picard finds out Jessica has been murdered and feels sorry he couldn't have stopped it, even though she's just a holodeck character. Picard (as Hill) was later accused by two police officers of murdering Jessica. (TNG: "The Big Goodbye")

Jessica Bradley was played by Carolyn Allport. Although anything from the holodeck supposedly dematerializes upon leaving the holodeck, Doctor Crusher is seen in the observation lounge wiping off the lipstick from Picard after being kissed by the holodeck character Jessica Bradley.