Prema II is the second planet in the Prema system and site of a Talaxian mining colony.

In 2372, the colonists agreed to help the USS Voyager in the event of a Kazon attack. (VOY: "Basics, Part I")

After Voyager was captured by the Kazon-Nistrim, two fighters from Prema II assisted in Tom Paris' plan to retake the ship. (VOY: "Basics, Part II")