Shenandoah

From Memory Alpha, the free Star Trek reference

You may be looking for the Danube-class runabout USS Shenandoah.

The Shenandoah was an Earth starship that was in service during the 2150s, under command of captain Duvall.

Among the news that was received by the Enterprise (NX-01) from Earth in September 2151, was word that Duvall was promoted as the CO of the Shenandoah. Upon learning this, Enterprise Captain Jonathan Archer was surprised, commenting, "thank God we're a hundred light years away." (ENT: "Silent Enemy")